The History of HGH
Human Growth Hormone is a substance created by the pituitary gland in children and adolescent youth that stimulates the production of growth and cell reproduction, primarily in height growth.
Human Growth Hormone primarily stimulates division and multiplication of cartilage and chondrocytes (cells in the growing ends of children’s long bones (legs, arms, fingers and toes). HGH also acts on the liver to stimulate the production of Insulin-Like Growth Factor I (IGF-I). IGF-I also promotes bone growth. The level of HGH and IGF-I tends to decrease with age.
In 1982, the book “Life Extension: A Practical Scientific Approach” by Durk Pearson and Sandy Shaw was published. This book was the first to claim that through amino acids, vitamins, minerals and other compounds’ consumpsion would result in weight loss, lean muscle production and generally be life prolonging.
The book had no real scientific basis however vitamin and amino acid sales increased significantly after the publishing of the book.
Eight years later, The New England Journal of Medicine published an article that a study had been conducted on 12 men for six months and the results were an 8.8% increase in in lean body mass, and a 14.4% decrease in body fat.
This article stimulated the HGH supplement market. “Companies” were popping up all over (the Internet) selling HGH supplements. It is important to understand that companies that are marketing “HGH supplements” over-the-counter are citing this same study, which was conducted with HGH injections.
In 1993 the American Association for Anti-Aging Medicine (A4M) was formed. They laid claim that HGH related products were questionable. HGH releasers, oral hormone products, which would not work because the HGH would be digested instead of absorbed into the blood stream, were discounted and not recommended by A4M.
In 2003, The New England Journal of Medicine denounced the 1990 article. This was a bold action by the journal. They placed the entire content of both articles so Internet readers could make informed decisions.
They also published related articles that were written after the 1990 article were several studies showed significant side effects and that they may have shown growth in body composition but did not show significant improvement on function.
Also in 2003, the FDA sent an objection letter to “Be Youthful”, a producer of an HGH product, claiming it was a treatment for high cholesterol, high blood pressure, depression and fatigue.
The FDA also notified “Nature’s Youth, LCC” that claims made for the product, that they marketed as an HGH releaser, was unsubstantiated and illegal. They destroyed 5,700 boxes of the product.
In 2005, Dr. Edmund Chein was place on probation and a $10,000 fine in the state of California for specializing in “optimized total hormone balancing by returning hormone levels to values consistant with a younger person.” The grounds for the case included prescribing HGH and Insulin to a patient who did not have diabetes nor was the patient HGH deficient.
If you choose to use an HGH product, seek a doctor’s advice before self-administering growth hormone or “HGH producing supplements” to ensure all of your options are considered.
|